Solid Democratic (8)
- Reed (Rhode Island)
- Coons (Delaware)
- Durbin (Illinois)*
- Schatz (Hawaii)**
- T. Udall (New Mexico)
- Markey (Massachusetts)
- Reed (Rhode Island)
- Merkley (Oregon)
- Open New Jersey (Chiesa)
- M. Udall (Colorado)
- Open Iowa (Harkin)
- Shaheen (New Hampshire)
- Franken (Minnesota)
- Open Michigan (Levin)
- Hagan (North Carolina)
- Open Montana (Baucus)
- Landrieu (Louisiana)
- Begich (Alaska)
- Pryor (Arkansas)
Leans Republican (2)
- McConnell (Kentucky)
- Open West Virginia (Rockefeller)
- Open South Dakota (Johnson)
- Cornyn (Texas)
- Open Georgia (Chambliss)
- Collins (Maine)*
Safe Republican (9)
- Open Nebraska (Johanns)
- Risch (Idaho)
- Cochran (Mississippi)
- Alexander (Tennessee)
- Sessions (Alabama)
- Graham (South Carolina)
- Scott (South Carolina-B)
- Roberts (Kansas)*
- Inhofe (Oklahoma)
(Updates)
(7/01/2013) List Creation
*Denotes potential retirement
**Competitive primary between Colleen Hanabusa and Brian Schatz (Seat originally vacated by the death of Daniel Inouye